Publications
2000
Since
0
Scientific output
2023
Cao, L., Schoenmaker, L., Ten Den, S. A. , Passier, R. , Schwach, V., & Verbeek, F. J. (2023). Automated Sarcomere Structure Analysis for Studying Cardiotoxicity in Human Pluripotent Stem Cell-Derived Cardiomyocytes. Microscopy and microanalysis, 29(1), 254-264. https://doi.org/10.1093/micmic/ozac016
Rivera-Arbeláez, J. M., Keekstra, D., Cofiño-Fabres, C., Boonen, T., Dostanic, M., ten Den, S. A., Vermeul, K., Mastrangeli, M. , van den Berg, A. , Segerink, L. I., Ribeiro, M. C. , Strisciuglio, N. , & Passier, R. (2023). Automated assessment of human engineered heart tissues using deep learning and template matching for segmentation and tracking. Bioengineering and Translational Medicine, 8(3), [e10513]. https://doi.org/10.1002/btm2.10513
Trikalitis, V. D., Kroese, N. J. J. , Kaya, M., Cofino Fabres, C., ten Den, S. A. , S.M. Khalil, I. , Misra, S. , Koopman, B. F. J. M. , Passier, R. , Schwach, V. , & Rouwkema, J. (2023). Embedded 3D printing of dilute particle suspensions into dense complex tissue fibers using shear thinning xanthan baths. Biofabrication, 15(1), [015014]. https://doi.org/10.1088/1758-5090/aca124
Rivera Arbeláez, J. M. (2023). Following the dots: Versatile and modular approach for engineering and analyzing three-dimensional cardiac tissues. [PhD Thesis – Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036555272
de Graaf, M. N. S. , Vivas, A., Kasi, D. G., van den Hil, F. E. , van den Berg, A. , van der Meer, A. D. , Mummery, C. L., & Orlova, V. V. (2023). Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip. Lab on a chip, 23(1), 168-181. https://doi.org/10.1039/d2lc00686c
Broccoli, A. , Vollertsen, A. R., Roels, P., van Vugt, A. , van den Berg, A. , & Odijk, M. (2023). Nanoparticle Printing for Microfluidic Applications: Bipolar Electrochemistry and Localized Raman Sensing Spots. Micromachines, 14(2), [453]. https://doi.org/10.3390/mi14020453
2022
Ribeiro, M. C. , Rivera-Arbelaez, J. M. , Cofino-Fabres, C. , Schwach, V. , Slaats, R. H. , ten Den, S. A. , Vermeul, K. , van den Berg, A., Perez-Pomares, J. M. , Segerink, L. I., Guadix, J. A. , & Passier, R. (2022). A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues. Journal of Personalized Medicine, 12(2), [214]. https://doi.org/10.3390/jpm12020214
Harlaar, N., Dekker, S. O., Zhang, J., Snabel, R. R., Veldkamp, M. W., Verkerk, A. O. , Fabres, C. C. , Schwach, V., Lerink, L. J. S., Rivaud, M. R., Mulder, A. A., Corver, W. E., Goumans, M. J. T. H., Dobrev, D., Klautz, R. J. M., Schalij, M. J., Veenstra, G. J. C. , Passier, R., van Brakel, T. J., … de Vries, A. A. F. (2022). Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Nature Biomedical Engineering, 6, 389-402. https://doi.org/10.1038/s41551-021-00827-5
Komen, J. , van den Berg, A. , van der Meer, A., & Van Vuurden, D. (2022). Effect of dynamic, intracerebral-like, doxorubicin concentrations on brain stem cancer cells on-chip. Poster session presented at Microphysiological Systems World Summit, MPS 2022, New Orleans, Louisiana, United States.
Vivas, A. , van den Berg, A. , Passier, R. , Odijk, M. , & van der Meer, A. D. (2022). Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-on-chips. Lab on a chip, 22(6), 1231-1243. https://doi.org/10.1039/d1lc00999k
Vivas, A., IJspeert, C., Pan, J. Y. , Vermeul, K. , van den Berg, A. , Passier, R., Keller, S. S. , & van der Meer, A. D. (2022). Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture. Advanced Materials Technologies. https://doi.org/10.1002/admt.202101355
Mostert, D., Masdeu, I. J. , Passier, R. P. C. J. J., Kurniawan, N. A., & Bouten, C. V. C. (2022). Mechanical constraint model to understand remodeling in beating cardiac microtissues. Biophysical journal, 121(3), 263A-264A. https://doi.org/10.1016/j.bpj.2021.11.1413
Komen, J., van Neerven, S. , Bossink, E. G. B. M., de Groot, N., Nijman, L. , van den Berg, A., Vermeulen, L. , & van der Meer, A. (2022). The Effect of Dynamic, In Vivo-like Oxaliplatin on HCT116 Spheroids in a Cancer-on-Chip Model Is Representative of the Response in Xenografts. Micromachines, 13(5), [739]. https://doi.org/10.3390/mi13050739
2021
Middelkamp, H. H. T. , van den Berg, A. , & van der Meer, A. D. (2021). 3D Blood Vessels-on-Chip for atherosclerosis modelling. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 16931694)
Cioffi, F., Adam, R. H. I. , Bansal, R. , & Broersen, K. (2021). A review of oxidative stress products and related genes in early alzheimer’s disease. Journal of Alzheimer’s Disease, 83(3), 977-1001. https://doi.org/10.3233/JAD-210497
Rao, A. , Kumar, S. , Annink, C. , Le, D. A., Chinnaj, S., Alotaibi, M. B. , Sîretanu, I. , Duits, M., Yousef, A. A. , & Mugele, F. (2021). Artificial Diagenesis of Carbonates: Temperature-Dependent Inorganic and Organic Modifications in Reservoir Mimetic Fluids. SPE journal, 26(05), 3222-3236. [SPE-200331-PA]. https://doi.org/10.2118/200331-PA
Bossink, E. G. B. M. , Vollertsen, A. R. , Segerink, L. , van der Meer, A. , & Odijk, M. (2021). Automated medium recirculation using macro valves for high flow rates in an endothelial cell culture chip. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1269-1270)
Middelkamp, H. H. T., Verboven, A. H. A. , De sa Vivas, A. G., Schoenmaker, C., Klein Gunnewiek, T. M. , Passier, R., Albers, C. A., ‘t Hoen, P. A. C., Nadif Kasri, N. , & van der Meer, A. D. (2021). Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips. Scientific reports, 11(1), [2281]. https://doi.org/10.1038/s41598-021-81933-x
Arik, Y. B. , De Sa Vivas, A., Laarveld, D., Van Laar, N., Gemser, J., Visscher, T. , Van Den Berg, A. , Passier, R. , & Van Der Meer, A. D. (2021). Collagen i Based Enzymatically Degradable Membranes for Organ-on-a-Chip Barrier Models. ACS Biomaterials Science and Engineering, 7(7), 2998-3005. https://doi.org/10.1021/acsbiomaterials.0c00297
Komen, J. , Bossink, E. G. B. M. , van den Berg, A. , & van der Meer, A. (2021). Comparing on-chip colorectal cancer spheroid drug response to xenografts. Poster session presented at EUROoCS Conference 2021.
Vaneyck, J. , Segers-Nolten, I. , Broersen, K. , & Claessens, M. M. A. E. (2021). Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins. Journal of biological chemistry, 296, [100358]. https://doi.org/10.1016/J.JBC.2021.100358
van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. In Proceedings of the 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 (pp. 495-496)
van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. Poster session presented at 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021, Palm Springs, California, United States.
Zeijen, N. J. L. (2021). Directing cell differentiation in organ-on-chip devices through microarchitecture and supported lipid bilayers. University of Twente. https://doi.org/10.3990/1.9789036551908
Stein, J. M. , Mummery, C. L., & Bellin, M. (2021). Engineered models of the human heart: directions and challenges. Stem cell reports, 16(9), 2049-2057. https://doi.org/10.1016/j.stemcr.2020.11.013
Vollertsen, A. R. , Vivas, A., van Meer, B. , van den Berg, A. , Odijk, M. , & van der Meer, A. D. (2021). Facilitating implementation of organs-on-chips by open platform technology. Biomicrofluidics, 15(5), [051301]. https://doi.org/10.1063/5.0063428
Vivas, A. , Berg, A. V. D. , Passier, R. , Odijk, M. , & Meer, A. D. V. D. (2021). Fluidic Circuit Board with Modular Sensor and Valves Enables Stand-Alone, Tubeless Microfluidic Flow Control in Organs-on-Chips. bioRxiv. https://doi.org/10.1101/2021.11.24.469685
Vollertsen, A. R. , Den, S. A. T. , Schwach, V. , van den Berg, A. , Passier, R. , van der Meer, A. D. , & Odijk, M. (2021). Highly parallelized human embryonic stem cell differentiation to cardiac mesoderm in nanoliter chambers on a microfluidic chip. Biomedical microdevices, 23(2), [30]. https://doi.org/10.1007/s10544-021-00556-1
Coenen, D. M., Heinzmann, A. C. A., Oggero, S. , Albers, H. J., Nagy, M., Hagué, P., Kuijpers, M. J. E., Vanderwinden, J. M. , van der Meer, A. D., Perretti, M., Koenen, R. R., & Cosemans, J. M. E. M. (2021). Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. Cells, 10(8), [1998]. https://doi.org/10.3390/cells10081998
Broccoli, A. , Vollertsen, A. R., Roels, P., van Vugt, A. , van den Berg, A. , & Odijk, M. (2021). Local deposition of nanoparticles on a PDMS Microfluidic device. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 – 14 October 2021, Palm Springs, CA, USA (pp. 1381-1382)
Tanumihardja, E. , Slaats, R. H. , van der Meer, A. D. , Passier, R. , Olthuis, W. , & van den Berg, A. (2021). Measuring both pH and O2 with a single on-chip sensor in cultures of human pluripotent stem cell-derived cardiomyocytes to track induced changes in cellular metabolism. ACS sensors, 6(1), 267-274. https://doi.org/10.1021/acssensors.0c02282
Arik, Y. B. , Buijsman, W. , Loessberg-Zahl, J. T. , Cuartas Velez, C. A. , Veenstra, C., Logtenberg, S., Grobbink, A. M. , Bergveld, P., Gagliardi, G., den Hollander, A. I. , Bosschaart, N. , van den Berg, A. , Passier, R. , & van der Meer, A. (2021). Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant readouts for tissue permeability and vascular structure. Lab on a chip, 21(2), 272-283. https://doi.org/10.1039/d0lc00639d
Komen, J., van Neerven, S. M. , van den Berg, A., Vermeulen, L. , & van der Meer, A. D. (2021). Mimicking and surpassing the xenograft model with cancer-on-chip technology. EBioMedicine, 66, [103303]. https://doi.org/10.1016/j.ebiom.2021.103303
Slaats, R. H. (2021). Modelling the human heart: Human stem cell-based models lead the way in physiological, pathological, and toxicological research. University of Twente. https://doi.org/10.3990/1.9789036552318
Tanumihardja, E. , de Bruijn, D. S. , Slaats, R. H. , Olthuis, W. , & van den Berg, A. (2021). Monitoring contractile cardiomyocytes via impedance using multipurpose thin film ruthenium oxide electrodes. Sensors (Switzerland), 21(4), [1433]. https://doi.org/10.3390/s21041433
Bossink, E. G. B. M. , Vollertsen, A. R., Hagen , L. P. , van der Meer, A. , Segerink, L. , & Odijk, M. (2021). Multiplexed Organ-on-Chips with integrated macro valves for automated cell culture. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021 (pp. 1385-1386)
Paloschi, V., Sabater-Lleal, M. , Middelkamp, H. H. T. , De sa Vivas, A. G., Johansson, S. , van der Meer, A., Tenje, M., & Maegdefessel, L. (2021). Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research, 117(14), 2742-2754. https://doi.org/10.1093/cvr/cvab088
Low, L. A. , Mummery, C., Berridge, B. R., Austin, C. P., & Tagle, D. A. (2021). Organs-on-chips: into the next decade. Nature Reviews Drug Discovery, 20(5), 345-361. https://doi.org/10.1038/s41573-020-0079-3
Schneider, S., Bubeck, M., Rogal, J. , Weener, H. J., Rojas, C., Weiss, M., Heymann, M. , van der Meer, A. D., & Loskill, P. (2021). Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems. Lab on a chip, 21(20), 3963-3978. https://doi.org/10.1039/d1lc00494h
Marasco, D., Vicidomini, C., Krupa, P. , Cioffi, F., Huy, P. D. Q., Li, M. S., Florio, D. , Broersen, K., De Pandis, M. F., & Roviello, G. N. (2021). Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation. Chemico-Biological Interactions, 334, [109300]. https://doi.org/10.1016/j.cbi.2020.109300
Hoefer, T., Rana, A., Niego, B., Jagdale, S. , Albers, H. J., Gardiner, E. E., Andrews, R. K. , Van der Meer, A. D., Hagemeyer, C. E., & Westein, E. (2021). Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro. Haematologica, 106(11). https://doi.org/10.3324/haematol.2020.250761
Zakharova, M. , Tibbe, M. P. , Koch, L. S. , Le-The, H. , Leferink, A. M. , van den Berg, A. , van der Meer, A. D. , Broersen, K. , & Segerink, L. I. (2021). Transwell-Integrated 2 µm Thick Transparent Polydimethylsiloxane Membranes with Controlled Pore Sizes and Distribution to Model the Blood-Brain Barrier. Advanced Materials Technologies, 6(12), [2100138]. https://doi.org/10.1002/admt.202100138
2020
Catarino Ribeiro, M. , Slaats, R. H. , Schwach, V. , Rivera Arbelaez, J. M., Tertoolen, L. G. J., Van Meer, B. J. , Molenaar, R. , Mummery, C. L. , Claessens, M. M. A. E. , & Passier, R. (2020). A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness. Journal of molecular and cellular cardiology, 141, 54-64. https://doi.org/10.1016/j.yjmcc.2020.03.008
Cao, L. , Der Meer, A. D. V., Verbeek, F. J. , & Passier, R. (2020). Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes. BMC bioinformatics, 21(1), [187]. https://doi.org/10.1186/s12859-020-3466-1
Saleem, U., Meer, B. J. V., Katili, P. A., Yusof, N. A. N. M., Mannhardt, I., Krotenberg Garcia, A., Tertoolen, L., Korte, T. D., Vlaming, M. L. H., McGlynn, K., Nebel, J., Bahinski, A., Harris, K., Rossman, E., Xu, X., Burton, F. L., Smith, G. L., Clements, P. , Mummery, C. L., … Denning, C. (2020). Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes. Toxicological Sciences, 176(1), 103-123. https://doi.org/10.1093/toxsci/kfaa058
Komen, J. , Westerbeek, E. Y. , Kolkman, R. W., Roesthuis, J. , Lievens, C. , van den Berg, A. , & van der Meer, A. D. (2020). Controlled pharmacokinetic anti-cancer drug concentration profiles lead to growth inhibition of colorectal cancer cells in a microfluidic device. Lab on a chip, 20(17), 3167-3178. https://doi.org/10.1039/d0lc00419g
Schilder, W. H. , Tanumihardja, E. , Leferink, A. M. , van den Berg, A. , & Olthuis, W. (2020). Determining the antioxidant properties of various beverages using staircase voltammetry. Heliyon, 6(6), [e04210]. https://doi.org/10.1016/j.heliyon.2020.e04210
Das, P., Remigy, J. C., Lahitte, J. F. , van der Meer, A. D., Garmy-Susini, B., Coetsier, C., Desclaux, S., & Bacchin, P. (2020). Development of double porous poly (ε – caprolactone)/chitosan polymer as tissue engineering scaffold. Materials Science and Engineering C, 107, [110257]. https://doi.org/10.1016/j.msec.2019.110257
Schwach, V., Gomes Fernandes, M., Maas, S., Gerhardt, S., Tsonaka, R., Van Der Weerd, L. , Passier, R. , Mummery, C. L., Birket, M. J., & Salvatori, D. C. F. (2020). Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction. Cardiovascular Research, 116(3), 545-553. https://doi.org/10.1093/cvr/cvz181
Cao, X., van den Hil, F. E. , Mummery, C. L., & Orlova, V. V. (2020). Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells. Current Protocols in Stem Cell Biology, 52(1), [e108]. https://doi.org/10.1002/cpsc.108
Schwach, V. , Slaats, R. H. , & Passier, R. (2020). Human Pluripotent Stem Cell-Derived Cardiomyocytes for Assessment of Anticancer Drug-Induced Cardiotoxicity. Frontiers in Cardiovascular Medicine, 7, 1-12. [50]. https://doi.org/10.3389/fcvm.2020.00050
Giacomelli, E., Meraviglia, V., Campostrini, G., Cochrane, A., Cao, X., van Helden, R. W. J., Krotenberg Garcia, A., Mircea, M., Kostidis, S., Davis, R. P., van Meer, B. J., Jost, C. R., Koster, A. J., Mei, H., Míguez, D. G., Mulder, A. A., Ledesma-Terrón, M., Pompilio, G., Sala, L. , … Mummery, C. L. (2020). Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease. Cell stem cell, 26(6), 862-879.e11. https://doi.org/10.1016/j.stem.2020.05.004
Manz, X. D. , Albers, H. J., Symersky, P., Aman, J. , van der Meer, A. D., Bogaard, H. J., & Szulcek, R. (2020). In vitro microfluidic disease model to study whole blood-endothelial interactions and blood clot dynamics in real-time. Journal of visualized experiments, 159, [e61068]. https://doi.org/10.3791/61068
Allijn, I. , Ribeiro, M. , Poot, A. , Passier, R. , & Stamatialis, D. (2020). Membranes for modelling cardiac tissue stiffness in vitro based on poly(Trimethylene carbonate) and poly(ethylene glycol) polymers. Membranes, 10(10), 1-12. [274]. https://doi.org/10.3390/membranes10100274
Vollertsen, A. R. , de Boer, D. , Dekker, S., Wesselink, B. A. M. , Haverkate, R. , Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M. , Passier, R. , van den Berg, A. , van der Meer, A. D. , & Odijk, M. (2020). Modular operation of microfluidic chips for highly parallelized cell culture and liquid dosing via a fluidic circuit board. Microsystems and Nanoengineering, 6(1), [107]. https://doi.org/10.1038/s41378-020-00216-z
Zakharova, M., Palma do Carmo, M. A. , van der Helm, M. W. , Le-The, H., de Graaf, M. N. S., Orlova, V. , van den Berg, A. , van der Meer, A. D. , Broersen, K. , & Segerink, L. I. (2020). Multiplexed blood-brain barrier organ-on-chip. Lab on a chip, 20(17), 3132-3143. https://doi.org/10.1039/d0lc00399a
Loessberg-Zahl, J. T., Beumer, J. , van den Berg, A. , Eijkel, J. C. T. , & van der Meer, A. D. (2020). Patterning Biological Gels for 3D Cell Culture inside Microfluidic Devices by Local Surface Modification through Laminar Flow Patterning. Micromachines, 11(12), [1112]. https://doi.org/10.3390/mi11121112
2019
Komen, J. , Westerbeek, E. Y. , van der Meer, A. , & van den Berg, A. (2019). A microfluidic device for testing static and dynamic, in vivo like, drug concentration effects on cancer cells. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences
Campostrini, G., Sala, L., Ward-van Oostwaard, D., van Meer, B. J., Tertoolen, L. G. J., Bartulos-Encinas, O., Braam, S. R., IJzerman, A. P. , Mummery, C. L., & Bellin, M. (2019). A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes. Acta physiologica, 227(S718), 159-160. [e13366]. https://doi.org/10.1111/apha.13366
Cochrane, A. , Albers, H. J. , Passier, R. , Mummery, C. L. , van den Berg, A., Orlova, V. V. , & van der Meer, A. (2019). Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology. Advanced drug delivery reviews, 140, 68-77. https://doi.org/10.1016/j.addr.2018.06.007
Hubin, E., Verghese, P. B., van Nuland, N. , & Broersen, K. (2019). Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation. FEBS letters, 593(11), 1144-1153. https://doi.org/10.1002/1873-3468.13428
Avgidis, F. , Tibbe, M. P. , Leferink, A. M. , & Segerink, L. (2019). Asessing barrier properties using impedance spectroscopy in a semi-circular, blood-brain barrier on-chip. In Microtas 2019
Avgidis, F. , Tibbe, M. , Leferink, A. , & Segerink, L. (2019). Assessing barrier properties using impedance spectroscopy in a semi-circular, blood-brain barrier on-chip. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 422-423). (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019). The Chemical and Biological Microsystems Society.
Albers, H. J. , Passier, R. , van den Berg, A. , & van der Meer, A. D. (2019). Automated analysis of platelet aggregation on cultured endothelium in a microfluidic chip perfused with human whole blood. Micromachines, 10(11), [781]. https://doi.org/10.3390/mi10110781
Loessberg-Zahl, J. T. (2019). Developing microfluidic tooling for 3D cell-culture. University of Twente. https://doi.org/10.3990/1.9789036549202
Loessberg-Zahl, J. T., Gillrie, M., Kamm, R. D. , van den Berg, A. , van der Meer, A. , & Eijkel, J. C. T. (2019). Diffusion from steady-state profile (DSSP) for low cost, low concentration measurement of diffusion. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences: uTAS 2019 (pp. 1530-1531). The Chemical and Biological Microsystems Society.
Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S. , Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., … Schymkowitz, J. (2019). Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V. Protein engineering, design & selection : PEDS, 32(10), 443-457. https://doi.org/10.1093/protein/gzaa008
Loessberg-Zahl, J. , Van der Meer, A. D. , Van Den Berg, A. , & Eijkel, J. C. T. (2019). Flow focusing through gels as a tool to generate 3D concentration profiles in hydrogel-filled microfluidic chips. Lab on a chip, 19(2), 206-213. https://doi.org/10.1039/C8LC01140K
de Pinho, A. R. G., Odila, I. , Leferink, A. , van Blitterswijk, C., Camarero-Espinosa, S. , & Moroni, L. (2019). Hybrid polyester-hydrogel electrospun scaffolds for tissue engineering applications. Frontiers in bioengineering and biotechnology, 7(SEP), [231]. https://doi.org/10.3389/fbioe.2019.00231
Cioffi, F. (2019). Investigation into the molecular complexity of Alzheimer’s disease: an amyloid-ß centered approach. University of Twente. https://doi.org/10.3990/1.9789036548410
Cioffi, F., Adam, R. H. I. , & Broersen, K. (2019). Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease. Journal of Alzheimer’s Disease, 72(4), 981-1017. https://doi.org/10.3233/JAD-190863
Zakharova, M. , van der Helm, M., do Carmo, M. P. , Le-The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 432-433). The Chemical and Biological Microsystems Society.
Zakharova, M. , van der Helm, M., Palma Do Carmo, M. , Le The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. Poster session presented at 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019, Basel, Switzerland.
Schwach, V. , & Passier, R. (2019). Native cardiac environment and its impact on engineering cardiac tissue. Biomaterials Science, 7(9), 3566-3580. https://doi.org/10.1039/c8bm01348a
van der Helm, M. W., Henry, O. Y. F., Bein, A., Hamkins-Indik, T., Cronce, M. J., Leineweber, W. D. , Odijk, M. , van der Meer, A. D. , Eijkel, J. C. T., Ingber, D. E. , van den Berg, A. , & Segerink, L. I. (2019). Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy. Lab on a chip, 19(3), 452-463. https://doi.org/10.1039/c8lc00129d
Ng, P., Belgur, C., Barthakur, S. , van der Meer, A. D., Hamilton, G. A., & Barrile, R. (2019). Organs-on-Chips: a new paradigm for safety assessment of drug-induced thrombosis. Current Opinion in Toxicology, 17, 1-8. https://doi.org/10.1016/j.cotox.2019.08.004
Van Den Berg, A. , Mummery, C. L. , Passier, R. , & Van der Meer, A. D. (2019). Personalised organs-on-chips: functional testing for precision medicine. Lab on a chip, 19(2), 198-205. https://doi.org/10.1039/c8lc00827b
de Graf, M. N. S., Cochrane, A., van den Hil, F. E. , Buijsman, W. , van der Meer, A. , van den Berg, A. , Mummery, C. L., & Orlova, V. V. (2019). Scalable microphysiological system to model three-dimensional blood vessels. APL Bioengineering, 3(2), [026105]. https://doi.org/10.1063/1.5090986
Leferink, A. M. , Tibbe, M. P. , Bossink, E. G. B. M. , de Heus, L. E. , van Vossen, H. , van den Berg, A. , Moroni, L. , & Truckenmüller, R. K. (2019). Shape-defined solid micro-objects from poly(D,L-lactic acid) as cell-supportive counterparts in bottom-up tissue engineering. Materials Today Bio, 4, [100025]. https://doi.org/10.1016/j.mtbio.2019.100025
van Meer, B. J., Krotenberg, A., Sala, L., Davis, R. P., Eschenhagen, T., Denning, C., Tertoolen, L. G. J. , & Mummery, C. L. (2019). Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes. Nature communications, 10(1), [4325]. https://doi.org/10.1038/s41467-019-12354-8
Vollertsen, A. , Bossink, E., de Boer, D., Spalink, J. , Passier, R. , van den Berg, A. , Segerink, L. , van der Meer, A. , & Odijk, M. (2019). Standardized, modular microfluidic building blocks for automated cell culturing systems. In P. Diettrich, E. Delamarche, & A. Hierlemann (Eds.), 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (23 ed., pp. 86-87). The Chemical and Biological Microsystems Society.
Das, P. , van der Meer, A. D. , Vivas, A. , Arik, Y. B., Remigy, J. C., Lahitte, J. F. , Lammertink, R. G. H., & Bacchin, P. (2019). Tunable microstructured membranes in organs-on-chips to monitor transendothelial hydraulic resistance. Tissue Engineering – Part A, 25(23-24), 1635-1645. https://doi.org/10.1089/ten.tea.2019.0021
2018
Quiros-Solano, W. F., Gaio, N., Silvestri, C. , Arik, Y. B., Stassen, O. M. J. A. , Van Der Meer, A. D., Bouten, C. V. C. , Van Den Berg, A. , Dekker, R., & Sarro, P. M. (2018). A novel method to transfer porous PDMS membranes for high throughput Organ-on-Chip and Lab-on-Chip assembly. In 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018 (Vol. 2018-January, pp. 318-321). (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2018-January). IEEE. https://doi.org/10.1109/MEMSYS.2018.8346550
Pamies, D., Bal-Price, A., Chesne, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U. , Passier, R., Schwamborn, J. C., Stacey, G. N., Ellinger-Ziegelbauer, H., & Daneshian, M. (2018). Advanced Good Cell Culture Practice for Human Primary, Stem Cell-Derived and Organoid Models as well as Microphysiological Systems. Alternatives to Animal Experimentation, 35(3), 353-378. https://doi.org/10.14573/altex.1710081
Arık, Y. B. , van der Helm, M. W. , Odijk, M. , Segerink, L. I. , Passier, R. , van den Berg, A. , & van der Meer, A. D. (2018). Barriers-on-chips: Measurement of barrier function of tissues in organs-on-chips. Biomicrofluidics, 12(4), [042218]. https://doi.org/10.1063/1.5023041
Devalla, H. D. , & Passier, R. (2018). Cardiac differentiation of pluripotent stem cells and implications for modeling the heart in health and disease. Science Translational Medicine, 10(435), [eaah5457]. https://doi.org/10.1126/scitranslmed.aah5457
Sutton, K., El Haou, S., Williams, S., Devalla, H., Stoelzle-Feix, S., Juhasz, K., Doerr, L., Beckler, M., Haarmann, C., George, M. , Passier, R., Fertig, N., & Rogers, M. (2018). Differentiation and validation of human iPSC-derived atrial cardiomyocytes. Journal of Pharmacological and Toxicological Methods, 93, 168-168. [176]. https://doi.org/10.1016/j.vascn.2018.01.544
Koenrades, M. A. , Klein, A. , Leferink, A. M. , Slump, C. H. , & Geelkerken, R. H. (2018). Evolution of the Proximal Sealing Rings of the Anaconda Stent-Graft After Endovascular Aneurysm Repair. Journal of Endovascular Therapy, 25(4), 480-491. https://doi.org/10.1177/1526602818773085
Loessberg-Zahl, J. , van der Meer, A. D. , van den Berg, A. , & Eijkel, J. C. T. (2018). Flow Through Gels as a Tool to Generate 3D Concentration Profiles in Hydrogel-Filled Devices. In G-B. Lee, & F-G. T. (Eds.), MicroTAS 2018: The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2239-2241). The Chemical and Biological Microsystems Society.
Albers, H. J., da Silva Simão, J. P. , Middelkamp, H. H. T. , Mummery, C. L. , Passier, R. , van den Berg, A., Orlova, V. V. , & van der Meer, A. D. (2018). Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices. In F-G. Tseng, & G-B. Lee (Eds.), MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2392-2393). The Chemical and Biological Microsystems Society.
Tertoolen, L. G. J., Braam, S. R., van Meer, B. J. , Passier, R. , & Mummery, C. L. (2018). Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes. Biochemical and biophysical research communications, 497(4), 1135-1141. https://doi.org/10.1016/j.bbrc.2017.01.151
Le-The, H. , Tibbe, M. , Loessberg-Zahl, J., Palma Do Carmo, M. , van der Helm, M. , Bomer, J. , Van Den Berg, A. , Leferink, A. , Segerink, L. , & Eijkel, J. (2018). Large-scale fabrication of free-standing and sub-μm PDMS through-hole membranes. Nanoscale, 10(16), 7711-7718. https://doi.org/10.1039/c7nr09658e
Tibbe, M. P. , van der Meer, A. D. , van den Berg, A. , Stamatialis, D. , & Segerink, L. (2018). Membranes for Organs-on-Chips. In D. Stamatialis (Ed.), Biomedical Membranes and (Bio)Artificial Organs (pp. 295-321). World Scientific. https://doi.org/10.1142/9789813223974_0011
Das, P. (2018). Micro-structured membrane as a 3D biodegradable scaffold: development, characterization and cell-matrix interaction. Université Fédérale Toulouse Midi-Pyrénées. https://doi.org/10.3990/1.159058878
Quirós-Solano, W. F., Gaio, N., Stassen, O. M. J. A. , Arik, Y. B., Silvestri, C., Van Engeland, N. C. A. , van der Meer, A. , Passier, R., Sahlgren, C. M., Bouten, C. V. C. , van den Berg, A., Dekker, R., & Sarro, P. M. (2018). Microfabricated tuneable and transferable porous PDMS membranes for Organs-on-Chips. Scientific reports, 8(1), [13524]. https://doi.org/10.1038/s41598-018-31912-6
Halaidych, O. V., van den Hil, F. , Mummery, C. L., & Orlova, V. V. (2018). Microfluidic assay for the assessment of leukocyte adhesion to human induced pluripotent stem cell-derived endothelial cells (HiPSC-ECs). Journal of visualized experiments, 2018(141), [e58678]. https://doi.org/10.3791/58678
Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H. , … Mummery, C. L. (2018). Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. Circulation research, 122(3), e5-e16. https://doi.org/10.1161/CIRCRESAHA.117.312067
Barrile, R. , van der Meer, A. D., Park, H., Fraser, J. P., Simic, D., Teng, F., Conegliano, D., Nguyen, J., Jain, A., Zhou, M., Karalis, K., Ingber, D. E., Hamilton, G. A., & Otieno, M. A. (2018). Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clinical pharmacology & therapeutics, 104(6), 1240-1248. https://doi.org/10.1002/cpt.1054
Tibbe, M. P. , Le The, H. , Leferink, A. M. , Eijkel, J. C. T. , & Segerink, L. I. (2018). Porous sbum-micrometer PDMS membranes as cell culture substrates in a microfludiic chip. Poster session presented at 9th International Conference on Microtechnologies in Medicine and Biology, MMB 2018, Monterey, California, United States.
Jain, A., Barrile, R. , van der Meer, A. D., Mammoto, A., Mammoto, T., De Ceunynck, K., Aisiku, O., Otieno, M. A., Louden, C. S., Hamilton, G. A., Flaumenhaft, R., & Ingber, D. E. (2018). Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical pharmacology & therapeutics, 103(2), 332-340. https://doi.org/10.1002/cpt.742
van Meer, B. J., Sala, L., Tertoolen, L. G. J., Smith, G. L., Burton, F. L. , & Mummery, C. L. (2018). Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts. Current Protocols in Human Genetics, 99(1), [e67]. https://doi.org/10.1002/cphg.67
Minol, J. P., Reinsch, I., Luik, M. , Leferink, A., Barth, M., Assmann, A., Lichtenberg, A., & Akhyari, P. (2018). Reaktive Sauerstoffspezies und Gefäßdegeneration. Zeitschrift fur Herz-, Thorax- und Gefasschirurgie, 32(3), 242-247. https://doi.org/10.1007/s00398-018-0227-9
Vollertsen, A. R. , Dekker, S., Wesselink, B. A. M. , Haverkate, R. , Bomer, J. G. , Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M. , van der Meer, A. , Passier, R. , van den Berg, A. , & Odijk, M. (2018). Standardized, Modular Parallelization Platform for Microfluidic Large-Scale Integration Cell Culturing Chips. In F-G. Tseng, & G-B. Lee (Eds.), MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2199-2201). The Chemical and Biological Microsystems Society.
Mummery, C. (2018). The Next Chapter for Stem Cell Reports. Stem cell reports, 11(6), 1303-1304. https://doi.org/10.1016/j.stemcr.2018.10.021
Tibbe, M. , Le The, H. , Eijkel, J. , van den Berg, A. , Leferink, A. , & Segerink, L. (2018). Transwell integrated porous sub-micrometer PDMS membranes as alternative cell culture platform. Poster session presented at EMBS Micro and Nantechnology in Medicine Conference, MNMC 2018, Kauai, Hawaii, United States.
2017
Schwach, V., Verkerk, A. O., Mol, M., Monshouwer-Kloots, J. J., Devalla, H. D., Orlova, V. V., Anastassiadis, K. , Mummery, C. L., Davis, R. P. , & Passier, R. (2017). A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. Stem cell reports, 9(6), 1765-1779. https://doi.org/10.1016/j.stemcr.2017.10.024
Gümüscü, B. , Albers, H. J. , van den Berg, A. , Eijkel, J. , & van der Meer, A. D. (2017). A gut-on-a-chip study: Enabling on-demand manipulation of the outer cell microenvironment in a multicompartmental 3D culture array. In A. Lee, & D. DeVoe (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1013). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
Palma Do Carmo, M. , van der Helm, M. W. , van der Meer, A. , van den Berg, A. , Eijkel, J. C. T. , & Segerink, L. (2017). A multiplexed organ-on-chip device with individually addressable channels. Poster session presented at 2nd International Organ-on-Chip Symposium, IOOCS17, 2017, Lausanne, Switzerland.
Loessberg-Zahl, J. , Vollenbroek, J. , van der Meer, A. , Eijkel, J. , & van den Berg, A. (2017). Chipholder-integrated 3d-printed pneumatic logic controllers for microfluidic chips. In A. Lee, & D. DeVoe (Eds.), The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 645). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS(; Vol. 2017). The Chemical and Biological Microsystems Society.
Gümüscü, B. , Albers, H. J. , Van Den Berg, A. , Eijkel, J. C. T. , & Van Der Meer, A. D. (2017). Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery. Scientific reports, 7, [3381]. https://doi.org/10.1038/s41598-017-01944-5
Loessberg-Zahl, J., Makkinga, D. , van der Meer, A. , Eijkel, J. , & van den Berg, A. (2017). Configurable gel geometry via flow patterning for angiogenisis assays. In A. Lee, & D. D. (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1074-). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
van der Helm, M., Henry, O., Hamkins-Indik, T., Cronce, M., Leineweber, W. , Odijk, M. , van der Meer, A. , Eijkel, J., Ingber, D. E. , van den Berg, A. , & Segerink, L. (2017). Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip. In A. Lee, & D. DeVoe (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1114-1115). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
Sala, L., Ward-van Oostwaard, D., Tertoolen, L. G. J. , Mummery, C. L., & Bellin, M. (2017). Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs). Journal of visualized experiments, 2017(123), [e55587]. https://doi.org/10.3791/55587
van der Helm, M. W. , Odijk, M. , Frimat, J-P. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2017). Fabrication and validation of an organ-on-chip system with integrated electrodes to directly quantify transendothelial electrical resistance. Journal of visualized experiments, 127, [e56334]. https://doi.org/10.3791/56334
Guadix, J. A., Orlova, V. V., Giacomelli, E., Bellin, M. , Ribeiro, M. C. , Mummery, C. L., Pérez-Pomares, J. M. , & Passier, R. (2017). Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells. Stem cell reports, 9(6), 1754-1764. https://doi.org/10.1016/j.stemcr.2017.10.023
Rogers, M., Ridley, J., El-Haou, S., Williams, S., Webdale, L., Sutton, K., Stoelzle-Feix, S., Thomas, U., Fertig, N., Zwetsloot, T., Devalla, H. D. , & Passier, R. (2017). Human Ventricular Stem Cell Cardiomyocytes: Validating In Vitro Assays and Screening Platforms for Pro-arrhythmia Risk Prediction. Journal of Pharmacological and Toxicological Methods, 88(2), 241-241. [0237]. https://doi.org/10.1016/j.vascn.2017.09.238
Giacomelli, E. , Mummery, C. L., & Bellin, M. (2017). Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes. Cellular and Molecular Life Sciences, 74(20), 3711-3739. https://doi.org/10.1007/s00018-017-2546-5
Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., Saleem, U., Eschenhagen, T., Hortigon, M., Rodriguez, V. Z., Smith, G., van Meer, B., Tertoolen, L. , Mummery, C. , Catarino Ribeiro, M. , Passier, R., de Korte, T., Vlaming, M., Braam, S., … Denning, C. (2017). InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility. Journal of Pharmacological and Toxicological Methods, 88(2), 238-238. [0227]. https://doi.org/10.1016/j.vascn.2017.09.228
Sala, L., Bellin, M. , & Mummery, C. L. (2017). Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? British journal of pharmacology, 174(21), 3749-3765. https://doi.org/10.1111/bph.13577
Costa, P. F. , Albers, H. J., Linssen, J. E. A. , Middelkamp, H. H. T., van der Hout, L. , Passier, R. , Van Den Berg, A., Malda, J. , & van der Meer, A. D. (2017). Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data. Lab on a chip, 17(16), 2785-2792. https://doi.org/10.1039/c7lc00202e
Passier, R. (2017). Modelling and drug screening for cardiovascular disease. Acta physiologica, 219(S711), 7-7. [SO2-2]. https://doi.org/10.1111/apha.12866
van der Meer, A. (2017). Organs-on-chips for vascular function. Toxicology Letters, 280(1), S29. https://doi.org/10.1016/j.toxlet.2017.07.069
Molloy, C. P., Yao, Y., Kammoun, H., Bonnard, T., Hoefer, T., Alt, K., Tovar-Lopez, F., Rosengarten, G., Ramsland, P. A. , van der Meer, A. D. , van den Berg, A., Murphy, A. J., Hagemeyer, C. E., Peter, K., & Westein, E. (2017). Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation. Journal of thrombosis and haemostasis, 15(5), 972-982. https://doi.org/10.1111/jth.13666
van Meer, B. J., de Vries, H., Firth, K. S. A. , van Weerd, J., Tertoolen, L. G. J. , Karperien, H. B. J. , Jonkheijm, P., Denning, C., IJzerman, A. P. , & Mummery, C. L. (2017). Small molecule absorption by PDMS in the context of drug response bioassays. Biochemical and biophysical research communications, 482(2), 323-328. https://doi.org/10.1016/j.bbrc.2016.11.062
Giacomelli, E., Bellin, M., Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Orlova, V. V. , & Mummery, C. L. (2017). Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Development (Cambridge), 144(6), 1008-1017. https://doi.org/10.1242/dev.143438
Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., … Burton, F. L. (2017). Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. bioRxiv. https://doi.org/10.1101/160754
2016
den Hartogh, S. C., Wolstencroft, K. , Mummery, C. L. , & Passier, R. (2016). A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors. Scientific reports, 6, [19386]. https://doi.org/10.1038/srep19386
Jain, A. , van der Meer, A. D., Papa, A-L., Barrile, R., Lai, A., Schlechter, B. L., Otieno, M. A., Louden, C. S., Hamilton, G. A., Michelson, A. D., Frelinger, A. L., & Ingber, D. E. (2016). Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomedical microdevices, 18(73), 73-. [73]. https://doi.org/10.1007/s10544-016-0095-6
Mummery, C., Birket, M., van Meer, B. , Ribeiro, M. , Passier, R., Bellin, M., Orlova, V., Davis, G. R., Freund, C., Kosmidis, G., & Tertoolen, L. (2016). Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models. Human Gene Therapy, 27(11), A11-A11. [INV38]. https://doi.org/10.1089/hum.2016.29035.abstracts
Passier, R., Orlova, V. V. , & Mummery, C. (2016). Complex Tissue and Disease Modeling using hiPSCs. Cell stem cell, 18(3), 309-321. https://doi.org/10.1016/j.stem.2016.02.011
van der Helm, M. W. , Odijk, M. , Frimat, J-P. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2016). Direct quantification of transendothelial electrical resistance in organs-on-chips. Biosensors and bioelectronics, 85, 924-929. https://doi.org/10.1016/j.bios.2016.06.014
Herland, A. , van der Meer, A. D., Fitzgerald, E. A., Park, T-E., Sleeboom, J. J. F., & Ingber, D. E. (2016). Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. PLoS ONE, 11(3), -. [e0150360]. https://doi.org/10.1371/journal.pone.0150360
den Hartogh, S. C. , & Passier, P. C. J. J. (2016). Fluorescent Reporters in Human Pluripotent Stem Cells: Contributions to Cardiac Differentiation and Their Applications in Cardiac Disease and Toxicity. Stem cells, 34(1), 13-26. https://doi.org/10.1002/stem.2196
Schwach, V. , & Passier, R. (2016). Generation and purification of human stem cell-derived cardiomyocytes. Differentiation, 91(4-5), 126-138. https://doi.org/10.1016/j.diff.2016.01.001
Mummery, C. L. (2016). Go with the flow: humane stamcellen in vasculair onderzoek. Universiteit Twente.
van der Helm, M. W. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2016). Microfluidic organ-on-chip technology for blood-brain barrier research. Tissue barriers, 4(1), e1142493-. [e1142493]. https://doi.org/10.1080/21688370.2016.1142493
Middelkamp, H. H. T. , van der Meer, A. D. , Hummel, J. M. , Stamatialis, D. , Mummery, C. L. , Passier, P. C. J. J. , & IJzerman, M. J. (2016). Organs-on-Chips in Drug Development: The Importance of Involving Stakeholders in Early Health Technology Assessment. Applied in vitro toxicology, 2(2), 74-81. https://doi.org/10.1089/aivt.2015.0029
Karperien, H. B. J. , & Mummery, C. L. (2016). Stamcellen. Wetenschap, werkelijkheid en fictie. Stichting Bio-Wetenschappen en Maatschappij. http://www.biomaatschappij.nl/product/stamcellen-2/
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2015
Kosmidis, G., Bellin, M. , Ribeiro, M. C., van Meer, B., Ward-van Oostwaard, D. , Passier, R., Tertoolen, L. G. J. , Mummery, C. L., & Casini, S. (2015). Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure. Biochemical and biophysical research communications, 467(4), 998-1005. https://doi.org/10.1016/j.bbrc.2015.10.026
McKim, J. M. (Ed.) , van der Helm, M. W. , Broersen, K. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2015). Studying the blood-brain barrier on a microfluidic chip. Paper presented at In Vitro Toxicology Society Annual Meeting. https://doi.org/10.1089/aivt.2015.29000.abstracts
van der Helm, M. W. , Broersen, K. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2015). Studying the blood-brain barrier on a microfluidic chip. 313-314. Abstract from In Vitro Toxicology Society Annual Meeting. https://doi.org/10.1089/aivt.2015.29000.abstracts
van der Helm, M. W. , Broersen, K. , van der Meer, A. D. , Eijkel, J. C. T. , van den Berg, A. , & Segerink, L. I. (2015). Studying the blood-brain barrier on a microfluidic chip for drug development, pathology and toxicology. -. Poster session presented at Annual meeting of In Vitro Toxicological Society, Birmingham UK.