Publications

2000
Since
0
Scientific output

2023


Rivera-Arbeláez, J. M., Keekstra, D., Cofiño-Fabres, C., Boonen, T., Dostanic, M., ten Den, S. A., Vermeul, K., Mastrangeli, M. , van den Berg, A. , Segerink, L. I., Ribeiro, M. C. , Strisciuglio, N. , & Passier, R. (2023). Automated assessment of human engineered heart tissues using deep learning and template matching for segmentation and tracking. Bioengineering and Translational Medicine, 8(3), [e10513]. https://doi.org/10.1002/btm2.10513


Rivera Arbeláez, J. M. (2023). Following the dots: Versatile and modular approach for engineering and analyzing three-dimensional cardiac tissues. [PhD Thesis – Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036555272


 

2022

Ribeiro, M. C. , Rivera-Arbelaez, J. M. , Cofino-Fabres, C. , Schwach, V. , Slaats, R. H. , ten Den, S. A. , Vermeul, K. , van den Berg, A., Perez-Pomares, J. M. , Segerink, L. I., Guadix, J. A. , & Passier, R. (2022). A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues. Journal of Personalized Medicine, 12(2), [214]. https://doi.org/10.3390/jpm12020214
Harlaar, N., Dekker, S. O., Zhang, J., Snabel, R. R., Veldkamp, M. W., Verkerk, A. O. , Fabres, C. C. , Schwach, V., Lerink, L. J. S., Rivaud, M. R., Mulder, A. A., Corver, W. E., Goumans, M. J. T. H., Dobrev, D., Klautz, R. J. M., Schalij, M. J., Veenstra, G. J. C. , Passier, R., van Brakel, T. J., … de Vries, A. A. F. (2022). Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Nature Biomedical Engineering, 6, 389-402. https://doi.org/10.1038/s41551-021-00827-5
Komen, J. , van den Berg, A. , van der Meer, A., & Van Vuurden, D. (2022). Effect of dynamic, intracerebral-like, doxorubicin concentrations on brain stem cancer cells on-chip. Poster session presented at Microphysiological Systems World Summit, MPS 2022, New Orleans, Louisiana, United States.
Mostert, D., Masdeu, I. J. , Passier, R. P. C. J. J., Kurniawan, N. A., & Bouten, C. V. C. (2022). Mechanical constraint model to understand remodeling in beating cardiac microtissues. Biophysical journal, 121(3), 263A-264A. https://doi.org/10.1016/j.bpj.2021.11.1413
 

2021

Middelkamp, H. H. T. , van den Berg, A. , & van der Meer, A. D. (2021). 3D Blood Vessels-on-Chip for atherosclerosis modelling. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 16931694)
Bossink, E. G. B. M. , Vollertsen, A. R. , Segerink, L. , van der Meer, A. , & Odijk, M. (2021). Automated medium recirculation using macro valves for high flow rates in an endothelial cell culture chip. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1269-1270)
Komen, J. , Bossink, E. G. B. M. , van den Berg, A. , & van der Meer, A. (2021). Comparing on-chip colorectal cancer spheroid drug response to xenografts. Poster session presented at EUROoCS Conference 2021.
van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. In Proceedings of the 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 (pp. 495-496)
van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. Poster session presented at 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021, Palm Springs, California, United States.
Coenen, D. M., Heinzmann, A. C. A., Oggero, S. , Albers, H. J., Nagy, M., Hagué, P., Kuijpers, M. J. E., Vanderwinden, J. M. , van der Meer, A. D., Perretti, M., Koenen, R. R., & Cosemans, J. M. E. M. (2021). Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. Cells, 10(8), [1998]. https://doi.org/10.3390/cells10081998
Broccoli, A. , Vollertsen, A. R., Roels, P., van Vugt, A. , van den Berg, A. , & Odijk, M. (2021). Local deposition of nanoparticles on a PDMS Microfluidic device. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 – 14 October 2021, Palm Springs, CA, USA (pp. 1381-1382)
Bossink, E. G. B. M. , Vollertsen, A. R., Hagen , L. P. , van der Meer, A. , Segerink, L. , & Odijk, M. (2021). Multiplexed Organ-on-Chips with integrated macro valves for automated cell culture. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021 (pp. 1385-1386)
Paloschi, V., Sabater-Lleal, M. , Middelkamp, H. H. T. , De sa Vivas, A. G., Johansson, S. , van der Meer, A., Tenje, M., & Maegdefessel, L. (2021). Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research, 117(14), 2742-2754. https://doi.org/10.1093/cvr/cvab088
Low, L. A. , Mummery, C., Berridge, B. R., Austin, C. P., & Tagle, D. A. (2021). Organs-on-chips: into the next decade. Nature Reviews Drug Discovery, 20(5), 345-361. https://doi.org/10.1038/s41573-020-0079-3
Schneider, S., Bubeck, M., Rogal, J. , Weener, H. J., Rojas, C., Weiss, M., Heymann, M. , van der Meer, A. D., & Loskill, P. (2021). Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems. Lab on a chip, 21(20), 3963-3978. https://doi.org/10.1039/d1lc00494h
Marasco, D., Vicidomini, C., Krupa, P. , Cioffi, F., Huy, P. D. Q., Li, M. S., Florio, D. , Broersen, K., De Pandis, M. F., & Roviello, G. N. (2021). Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation. Chemico-Biological Interactions, 334, [109300]. https://doi.org/10.1016/j.cbi.2020.109300
Hoefer, T., Rana, A., Niego, B., Jagdale, S. , Albers, H. J., Gardiner, E. E., Andrews, R. K. , Van der Meer, A. D., Hagemeyer, C. E., & Westein, E. (2021). Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro. Haematologica, 106(11). https://doi.org/10.3324/haematol.2020.250761

2020

Saleem, U., Meer, B. J. V., Katili, P. A., Yusof, N. A. N. M., Mannhardt, I., Krotenberg Garcia, A., Tertoolen, L., Korte, T. D., Vlaming, M. L. H., McGlynn, K., Nebel, J., Bahinski, A., Harris, K., Rossman, E., Xu, X., Burton, F. L., Smith, G. L., Clements, P. , Mummery, C. L., … Denning, C. (2020). Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes. Toxicological Sciences, 176(1), 103-123. https://doi.org/10.1093/toxsci/kfaa058
Das, P., Remigy, J. C., Lahitte, J. F. , van der Meer, A. D., Garmy-Susini, B., Coetsier, C., Desclaux, S., & Bacchin, P. (2020). Development of double porous poly (ε – caprolactone)/chitosan polymer as tissue engineering scaffold. Materials Science and Engineering C, 107, [110257]. https://doi.org/10.1016/j.msec.2019.110257
Schwach, V., Gomes Fernandes, M., Maas, S., Gerhardt, S., Tsonaka, R., Van Der Weerd, L. , Passier, R. , Mummery, C. L., Birket, M. J., & Salvatori, D. C. F. (2020). Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction. Cardiovascular Research, 116(3), 545-553. https://doi.org/10.1093/cvr/cvz181
Cao, X., van den Hil, F. E. , Mummery, C. L., & Orlova, V. V. (2020). Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells. Current Protocols in Stem Cell Biology, 52(1), [e108]. https://doi.org/10.1002/cpsc.108
Giacomelli, E., Meraviglia, V., Campostrini, G., Cochrane, A., Cao, X., van Helden, R. W. J., Krotenberg Garcia, A., Mircea, M., Kostidis, S., Davis, R. P., van Meer, B. J., Jost, C. R., Koster, A. J., Mei, H., Míguez, D. G., Mulder, A. A., Ledesma-Terrón, M., Pompilio, G., Sala, L. , … Mummery, C. L. (2020). Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease. Cell stem cell, 26(6), 862-879.e11. https://doi.org/10.1016/j.stem.2020.05.004
Manz, X. D. , Albers, H. J., Symersky, P., Aman, J. , van der Meer, A. D., Bogaard, H. J., & Szulcek, R. (2020). In vitro microfluidic disease model to study whole blood-endothelial interactions and blood clot dynamics in real-time. Journal of visualized experiments, 159, [e61068]. https://doi.org/10.3791/61068
Zakharova, M., Palma do Carmo, M. A. , van der Helm, M. W. , Le-The, H., de Graaf, M. N. S., Orlova, V. , van den Berg, A. , van der Meer, A. D. , Broersen, K. , & Segerink, L. I. (2020). Multiplexed blood-brain barrier organ-on-chip. Lab on a chip, 20(17), 3132-3143. https://doi.org/10.1039/d0lc00399a
 

2019

Komen, J. , Westerbeek, E. Y. , van der Meer, A. , & van den Berg, A. (2019). A microfluidic device for testing static and dynamic, in vivo like, drug concentration effects on cancer cells. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences
Campostrini, G., Sala, L., Ward-van Oostwaard, D., van Meer, B. J., Tertoolen, L. G. J., Bartulos-Encinas, O., Braam, S. R., IJzerman, A. P. , Mummery, C. L., & Bellin, M. (2019). A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes. Acta physiologica, 227(S718), 159-160. [e13366]. https://doi.org/10.1111/apha.13366
Avgidis, F. , Tibbe, M. , Leferink, A. , & Segerink, L. (2019). Assessing barrier properties using impedance spectroscopy in a semi-circular, blood-brain barrier on-chip. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 422-423). (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019). The Chemical and Biological Microsystems Society.
Loessberg-Zahl, J. T., Gillrie, M., Kamm, R. D. , van den Berg, A. , van der Meer, A. , & Eijkel, J. C. T. (2019). Diffusion from steady-state profile (DSSP) for low cost, low concentration measurement of diffusion. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences: uTAS 2019 (pp. 1530-1531). The Chemical and Biological Microsystems Society.
Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S. , Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., … Schymkowitz, J. (2019). Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V. Protein engineering, design & selection : PEDS, 32(10), 443-457. https://doi.org/10.1093/protein/gzaa008
de Pinho, A. R. G., Odila, I. , Leferink, A. , van Blitterswijk, C., Camarero-Espinosa, S. , & Moroni, L. (2019). Hybrid polyester-hydrogel electrospun scaffolds for tissue engineering applications. Frontiers in bioengineering and biotechnology, 7(SEP), [231]. https://doi.org/10.3389/fbioe.2019.00231
Zakharova, M. , van der Helm, M., do Carmo, M. P. , Le-The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 432-433). The Chemical and Biological Microsystems Society.
Zakharova, M. , van der Helm, M., Palma Do Carmo, M. , Le The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. Poster session presented at 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019, Basel, Switzerland.
Ng, P., Belgur, C., Barthakur, S. , van der Meer, A. D., Hamilton, G. A., & Barrile, R. (2019). Organs-on-Chips: a new paradigm for safety assessment of drug-induced thrombosis. Current Opinion in Toxicology, 17, 1-8. https://doi.org/10.1016/j.cotox.2019.08.004
de Graf, M. N. S., Cochrane, A., van den Hil, F. E. , Buijsman, W. , van der Meer, A. , van den Berg, A. , Mummery, C. L., & Orlova, V. V. (2019). Scalable microphysiological system to model three-dimensional blood vessels. APL Bioengineering, 3(2), [026105]. https://doi.org/10.1063/1.5090986
van Meer, B. J., Krotenberg, A., Sala, L., Davis, R. P., Eschenhagen, T., Denning, C., Tertoolen, L. G. J. , & Mummery, C. L. (2019). Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes. Nature communications, 10(1), [4325]. https://doi.org/10.1038/s41467-019-12354-8
Vollertsen, A. , Bossink, E., de Boer, D., Spalink, J. , Passier, R. , van den Berg, A. , Segerink, L. , van der Meer, A. , & Odijk, M. (2019). Standardized, modular microfluidic building blocks for automated cell culturing systems. In P. Diettrich, E. Delamarche, & A. Hierlemann (Eds.), 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (23 ed., pp. 86-87). The Chemical and Biological Microsystems Society.
 

2018

Quiros-Solano, W. F., Gaio, N., Silvestri, C. , Arik, Y. B., Stassen, O. M. J. A. , Van Der Meer, A. D., Bouten, C. V. C. , Van Den Berg, A. , Dekker, R., & Sarro, P. M. (2018). A novel method to transfer porous PDMS membranes for high throughput Organ-on-Chip and Lab-on-Chip assembly. In 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018 (Vol. 2018-January, pp. 318-321). (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2018-January). IEEE. https://doi.org/10.1109/MEMSYS.2018.8346550
Pamies, D., Bal-Price, A., Chesne, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U. , Passier, R., Schwamborn, J. C., Stacey, G. N., Ellinger-Ziegelbauer, H., & Daneshian, M. (2018). Advanced Good Cell Culture Practice for Human Primary, Stem Cell-Derived and Organoid Models as well as Microphysiological Systems. Alternatives to Animal Experimentation, 35(3), 353-378. https://doi.org/10.14573/altex.1710081
Sutton, K., El Haou, S., Williams, S., Devalla, H., Stoelzle-Feix, S., Juhasz, K., Doerr, L., Beckler, M., Haarmann, C., George, M. , Passier, R., Fertig, N., & Rogers, M. (2018). Differentiation and validation of human iPSC-derived atrial cardiomyocytes. Journal of Pharmacological and Toxicological Methods, 93, 168-168. [176]. https://doi.org/10.1016/j.vascn.2018.01.544
Loessberg-Zahl, J. , van der Meer, A. D. , van den Berg, A. , & Eijkel, J. C. T. (2018). Flow Through Gels as a Tool to Generate 3D Concentration Profiles in Hydrogel-Filled Devices. In G-B. Lee, & F-G. T. (Eds.), MicroTAS 2018: The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2239-2241). The Chemical and Biological Microsystems Society.
Albers, H. J., da Silva Simão, J. P. , Middelkamp, H. H. T. , Mummery, C. L. , Passier, R. , van den Berg, A., Orlova, V. V. , & van der Meer, A. D. (2018). Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices. In F-G. Tseng, & G-B. Lee (Eds.), MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2392-2393). The Chemical and Biological Microsystems Society.
Tibbe, M. P. , van der Meer, A. D. , van den Berg, A. , Stamatialis, D. , & Segerink, L. (2018). Membranes for Organs-on-Chips. In D. Stamatialis (Ed.), Biomedical Membranes and (Bio)Artificial Organs (pp. 295-321). World Scientific. https://doi.org/10.1142/9789813223974_0011
Quirós-Solano, W. F., Gaio, N., Stassen, O. M. J. A. , Arik, Y. B., Silvestri, C., Van Engeland, N. C. A. , van der Meer, A. , Passier, R., Sahlgren, C. M., Bouten, C. V. C. , van den Berg, A., Dekker, R., & Sarro, P. M. (2018). Microfabricated tuneable and transferable porous PDMS membranes for Organs-on-Chips. Scientific reports, 8(1), [13524]. https://doi.org/10.1038/s41598-018-31912-6
Halaidych, O. V., van den Hil, F. , Mummery, C. L., & Orlova, V. V. (2018). Microfluidic assay for the assessment of leukocyte adhesion to human induced pluripotent stem cell-derived endothelial cells (HiPSC-ECs). Journal of visualized experiments, 2018(141), [e58678]. https://doi.org/10.3791/58678
Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H. , … Mummery, C. L. (2018). Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. Circulation research, 122(3), e5-e16. https://doi.org/10.1161/CIRCRESAHA.117.312067
Barrile, R. , van der Meer, A. D., Park, H., Fraser, J. P., Simic, D., Teng, F., Conegliano, D., Nguyen, J., Jain, A., Zhou, M., Karalis, K., Ingber, D. E., Hamilton, G. A., & Otieno, M. A. (2018). Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clinical pharmacology & therapeutics, 104(6), 1240-1248. https://doi.org/10.1002/cpt.1054
Tibbe, M. P. , Le The, H. , Leferink, A. M. , Eijkel, J. C. T. , & Segerink, L. I. (2018). Porous sbum-micrometer PDMS membranes as cell culture substrates in a microfludiic chip. Poster session presented at 9th International Conference on Microtechnologies in Medicine and Biology, MMB 2018, Monterey, California, United States.
Jain, A., Barrile, R. , van der Meer, A. D., Mammoto, A., Mammoto, T., De Ceunynck, K., Aisiku, O., Otieno, M. A., Louden, C. S., Hamilton, G. A., Flaumenhaft, R., & Ingber, D. E. (2018). Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical pharmacology & therapeutics, 103(2), 332-340. https://doi.org/10.1002/cpt.742
van Meer, B. J., Sala, L., Tertoolen, L. G. J., Smith, G. L., Burton, F. L. , & Mummery, C. L. (2018). Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts. Current Protocols in Human Genetics, 99(1), [e67]. https://doi.org/10.1002/cphg.67
Minol, J. P., Reinsch, I., Luik, M. , Leferink, A., Barth, M., Assmann, A., Lichtenberg, A., & Akhyari, P. (2018). Reaktive Sauerstoffspezies und Gefäßdegeneration. Zeitschrift fur Herz-, Thorax- und Gefasschirurgie, 32(3), 242-247. https://doi.org/10.1007/s00398-018-0227-9
Vollertsen, A. R. , Dekker, S., Wesselink, B. A. M. , Haverkate, R. , Bomer, J. G. , Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M. , van der Meer, A. , Passier, R. , van den Berg, A. , & Odijk, M. (2018). Standardized, Modular Parallelization Platform for Microfluidic Large-Scale Integration Cell Culturing Chips. In F-G. Tseng, & G-B. Lee (Eds.), MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2199-2201). The Chemical and Biological Microsystems Society.
Tibbe, M. , Le The, H. , Eijkel, J. , van den Berg, A. , Leferink, A. , & Segerink, L. (2018). Transwell integrated porous sub-micrometer PDMS membranes as alternative cell culture platform. Poster session presented at EMBS Micro and Nantechnology in Medicine Conference, MNMC 2018, Kauai, Hawaii, United States.
 

2017

Schwach, V., Verkerk, A. O., Mol, M., Monshouwer-Kloots, J. J., Devalla, H. D., Orlova, V. V., Anastassiadis, K. , Mummery, C. L., Davis, R. P. , & Passier, R. (2017). A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. Stem cell reports, 9(6), 1765-1779. https://doi.org/10.1016/j.stemcr.2017.10.024
Gümüscü, B. , Albers, H. J. , van den Berg, A. , Eijkel, J. , & van der Meer, A. D. (2017). A gut-on-a-chip study: Enabling on-demand manipulation of the outer cell microenvironment in a multicompartmental 3D culture array. In A. Lee, & D. DeVoe (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1013). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
Palma Do Carmo, M. , van der Helm, M. W. , van der Meer, A. , van den Berg, A. , Eijkel, J. C. T. , & Segerink, L. (2017). A multiplexed organ-on-chip device with individually addressable channels. Poster session presented at 2nd International Organ-on-Chip Symposium, IOOCS17, 2017, Lausanne, Switzerland.
Loessberg-Zahl, J. , Vollenbroek, J. , van der Meer, A. , Eijkel, J. , & van den Berg, A. (2017). Chipholder-integrated 3d-printed pneumatic logic controllers for microfluidic chips. In A. Lee, & D. DeVoe (Eds.), The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 645). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS(; Vol. 2017). The Chemical and Biological Microsystems Society.
Loessberg-Zahl, J., Makkinga, D. , van der Meer, A. , Eijkel, J. , & van den Berg, A. (2017). Configurable gel geometry via flow patterning for angiogenisis assays. In A. Lee, & D. D. (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1074-). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
van der Helm, M., Henry, O., Hamkins-Indik, T., Cronce, M., Leineweber, W. , Odijk, M. , van der Meer, A. , Eijkel, J., Ingber, D. E. , van den Berg, A. , & Segerink, L. (2017). Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip. In A. Lee, & D. DeVoe (Eds.), 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1114-1115). (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society.
Sala, L., Ward-van Oostwaard, D., Tertoolen, L. G. J. , Mummery, C. L., & Bellin, M. (2017). Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs). Journal of visualized experiments, 2017(123), [e55587]. https://doi.org/10.3791/55587
Guadix, J. A., Orlova, V. V., Giacomelli, E., Bellin, M. , Ribeiro, M. C. , Mummery, C. L., Pérez-Pomares, J. M. , & Passier, R. (2017). Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells. Stem cell reports, 9(6), 1754-1764. https://doi.org/10.1016/j.stemcr.2017.10.023
Rogers, M., Ridley, J., El-Haou, S., Williams, S., Webdale, L., Sutton, K., Stoelzle-Feix, S., Thomas, U., Fertig, N., Zwetsloot, T., Devalla, H. D. , & Passier, R. (2017). Human Ventricular Stem Cell Cardiomyocytes: Validating In Vitro Assays and Screening Platforms for Pro-arrhythmia Risk Prediction. Journal of Pharmacological and Toxicological Methods, 88(2), 241-241. [0237]. https://doi.org/10.1016/j.vascn.2017.09.238
Giacomelli, E. , Mummery, C. L., & Bellin, M. (2017). Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes. Cellular and Molecular Life Sciences, 74(20), 3711-3739. https://doi.org/10.1007/s00018-017-2546-5
Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., Saleem, U., Eschenhagen, T., Hortigon, M., Rodriguez, V. Z., Smith, G., van Meer, B., Tertoolen, L. , Mummery, C. , Catarino Ribeiro, M. , Passier, R., de Korte, T., Vlaming, M., Braam, S., … Denning, C. (2017). InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility. Journal of Pharmacological and Toxicological Methods, 88(2), 238-238. [0227]. https://doi.org/10.1016/j.vascn.2017.09.228
Molloy, C. P., Yao, Y., Kammoun, H., Bonnard, T., Hoefer, T., Alt, K., Tovar-Lopez, F., Rosengarten, G., Ramsland, P. A. , van der Meer, A. D. , van den Berg, A., Murphy, A. J., Hagemeyer, C. E., Peter, K., & Westein, E. (2017). Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation. Journal of thrombosis and haemostasis, 15(5), 972-982. https://doi.org/10.1111/jth.13666
van Meer, B. J., de Vries, H., Firth, K. S. A. , van Weerd, J., Tertoolen, L. G. J. , Karperien, H. B. J. , Jonkheijm, P., Denning, C., IJzerman, A. P. , & Mummery, C. L. (2017). Small molecule absorption by PDMS in the context of drug response bioassays. Biochemical and biophysical research communications, 482(2), 323-328. https://doi.org/10.1016/j.bbrc.2016.11.062
Giacomelli, E., Bellin, M., Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Orlova, V. V. , & Mummery, C. L. (2017). Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Development (Cambridge), 144(6), 1008-1017. https://doi.org/10.1242/dev.143438
Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., … Burton, F. L. (2017). Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. bioRxiv. https://doi.org/10.1101/160754
 

2016

Jain, A. , van der Meer, A. D., Papa, A-L., Barrile, R., Lai, A., Schlechter, B. L., Otieno, M. A., Louden, C. S., Hamilton, G. A., Michelson, A. D., Frelinger, A. L., & Ingber, D. E. (2016). Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomedical microdevices, 18(73), 73-. [73]. https://doi.org/10.1007/s10544-016-0095-6
Mummery, C., Birket, M., van Meer, B. , Ribeiro, M. , Passier, R., Bellin, M., Orlova, V., Davis, G. R., Freund, C., Kosmidis, G., & Tertoolen, L. (2016). Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models. Human Gene Therapy, 27(11), A11-A11. [INV38]. https://doi.org/10.1089/hum.2016.29035.abstracts
Herland, A. , van der Meer, A. D., Fitzgerald, E. A., Park, T-E., Sleeboom, J. J. F., & Ingber, D. E. (2016). Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. PLoS ONE, 11(3), -. [e0150360]. https://doi.org/10.1371/journal.pone.0150360
Chen, Z., Xian, W., Bellin, M., Dorn, T., Tian, Q., Goedel, A., Dreizehnter, L., Schneider, C. M., Ward-van Oostwaard, D., Ng, J. K. M., Hinkel, R., Pane, L. S. , Mummery, C. L., Lipp, P., Moretti, A., Laugwitz, K-L., & Sinnecker, D. (2016). Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes. European heart journal, 38(4), 292–301. https://doi.org/10.1093/eurheartj/ehw189
Devalla, H. D., Gélinas, R., Aburawi, E. H., Beqqali, A., Goyette, P., Freund, C., Chaix, M. A., Tadros, R., Jiang, H., Le Béchec, A., Monshouwer-Kloots, J. J., Zwetsloot, T., Kosmidis, G., Latour, F., Alikashani, A., Hoekstra, M., Schlaepfer, J. , Mummery, C. L., Stevenson, B. , … Passier, R. (2016). TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT. EMBO molecular medicine, 8(12), 1390-1408. https://doi.org/10.15252/emmm.201505719
Arik, Y. B., Matsui, R. , Sarajlic, E., Takayama, Y. , Boom, B. A. , Berenschot, J. W. , le Gac, S. , Tas, N. R., & Fujita, H. (2016). Ultra-thin nanochannel-based liquid TEM cell for EELS analysis and high resolution imaging. In 2016 IEEE 29th International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 804-807). IEEE. https://doi.org/10.1109/MEMSYS.2016.7421751
Passier, P. C. J. J. (2016). Waar het hart vol van is. Universiteit Twente.
 

2015

Kosmidis, G., Bellin, M. , Ribeiro, M. C., van Meer, B., Ward-van Oostwaard, D. , Passier, R., Tertoolen, L. G. J. , Mummery, C. L., & Casini, S. (2015). Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure. Biochemical and biophysical research communications, 467(4), 998-1005. https://doi.org/10.1016/j.bbrc.2015.10.026